孩童若有3種以上過敏症狀，發展出嗜伊紅性食道炎的風險增加9倍！費城兒童醫院對13萬名孩童追蹤研究發現，擁有過敏症狀的幼童有較高機會發展出嗜伊紅性食道炎（EoE），一種嚴重慢性食物性過敏，患者會有吞嚥困難、胃食道逆流等症狀。費城小兒科醫師大衛博士表示，此研究證實，嗜伊紅性食道炎會發生在過敏進程的最後階段，他呼籲，過敏幼童應盡快進行EoE篩檢。
「EoE與傳統食物性過敏（花生過敏）不同，EoE並不致命，但罹患率高。」大衛博士向《科學日報》表示，EoE具有緩慢進展的症狀，例如吞嚥困難、食物梗塞和胃食道逆流等。而且醫生很難發現究竟是何種食物造成過敏，通常必須讓患者接受限制性飲食來查出過敏原，所以EoE有時會誤診、甚至到青春期才發現。
「兒科過敏醫生常以『過敏進行曲』比喻過敏的發展進程，整個階段常在幼童5歲前完成。」費城小兒科醫師希爾說，典型的發展從過敏行皮膚炎、過度到食物性過敏，最後發展出氣喘等呼吸道過敏。這是第一個證實EoE包含在「過敏進行曲」內的研究。
根據《科技新聞網》報導，該研究追蹤13萬名孩童成長至青春期，結果顯示，孩童若有3種以上過敏症，最後發展出嗜伊紅性食道炎的風險增加9倍，平均病發年齡是2.6歲，擁有EoE的孩童也有很高的機率罹患過敏性鼻炎（一種季節性呼吸道過敏症）。
「既然已經了解EoE發生在『過敏進行曲』最後階段，醫生若能治療好早期過敏症，就能防止EoE發生。」大衛博士呼籲，幼童擁有皮膚、食物、呼吸道過敏應盡早進行EoE篩檢。
If children have more than 3 allergic symptoms, the risk of developing eosinophilic esophagitis increases 9 times! A follow-up study of 130,000 children in Philadelphia Children's Hospital found that young children with allergic symptoms had a higher chance of developing eosinophilic esophagitis (EoE), a severe chronic food allergy with dysphagia and gastroesophageal reflux. And other symptoms. Philadelphia pediatrician Dr. David said the study confirmed that eosinophilic esophagitis occurs in the final stages of the allergic process, and he urged allergic children to undergo EoE screening as soon as possible.
"EoE is different from traditional food allergies (peanut allergy), EoE is not fatal, but the attack rate is high." Dr. David told Science Daily that EoE has symptoms of slow progression, such as dysphagia, food infarction and gastroesophageal Countercurrent and so on. Moreover, it is difficult for doctors to find out what kind of food is causing allergies. Usually, patients must receive a restrictive diet to detect allergens, so EoE is sometimes misdiagnosed and even discovered during puberty.
"Pediatric allergy doctors often use "allergic marches" to describe the development of allergies. The whole stage is often completed before the child is 5 years old." Philadelphia pediatrician Hill said that the typical development from allergic dermatitis, excessive to food allergies, Finally, respiratory allergies such as asthma were developed. This is the first study to confirm that EoE is included in the Allergy March.
According to the Science and Technology News Network, the study tracked the growth of 130,000 children to puberty. The results showed that if children had more than 3 allergies, the risk of developing eosinophilic esophagitis increased by 9 times, the average age of onset. It is 2.6 years old and children with EoE also have a high probability of developing allergic rhinitis (a seasonal respiratory allergy).
"Since I know that EoE is in the final stages of the Allergy March, doctors can prevent EoE if they can treat early allergies." Dr. David called for young children to have skin, food, and respiratory allergies. EoE screening should be done as soon as possible. .
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